TMN355

Item no.	HY-107635-5mg
Manufacturer	MedChem Express
CASRN	1186372-20-2
Amount	5 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.67
Citations	[1]Ramachandran S, et al. Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. Cardiovasc Diabetol. 2016 Nov 3;15(1):152.
Smiles	O=C(NC(NC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C4=C(F)C=CC=C4Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1186372-20-2
Similar products	1186372-20-2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Cyclophilin
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	380.80
Product Description	TMN355 is a potent chemical cyclophilin A inhibitor and reduces foam cell formation and cytokine secretion. TMN355 is used for atherosclerosis[1].
Manufacturer - Research Area	Cardiovascular Disease
Solubility	DMSO: 31.25 mg/mL (ultrasonic)
Manufacturer - Pathway	Immunology/Inflammation
Isoform	Cyclophilin A
Clinical information	No Development Reported

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HY-107635-5mg-safety-datasheet.pdf