Comparison

Aminooxyacetic acid (hemihydrochloride) European Partner

Item no. HY-107994-500mg
Manufacturer MedChem Express
CASRN 2921-14-4
Amount 500 mg
Quantity options 10 mM/1 mL 1 g 500 mg
Category
Type Inhibitors
Specific against other
Purity 98.00
Citations [1]Wang C, et al. Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis. Cancer Lett. 2016 Aug 1;378(1):1-7.|[2]Pagliusi SR, et al. Aminooxyacetic acid induced accumulation of GABA in the rat brain. Interaction with GABA receptors and distribution in compartments. Naunyn Schmiedebergs Arch Pharmacol. 1983 Apr;322(3):210-5.|[3]Korangath P, et al. Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate. Clin Cancer Res. 2015 Jul 15;21(14):3263-73.
Smiles OC(CON)=O.[H]Cl.[1/2]
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Carboxymethoxylamine (hemihydrochloride),Aminooxyacetate (hemihydrochloride)
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
GABA Receptor
Shipping Temperature
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight
109.30
Product Description
Aminooxyacetic acid (Carboxymethoxylamine) hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T.
Manufacturer - Research Area
Cancer
Solubility
DMSO: 125 mg/mL (ultrasonic)|H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Membrane Transporter/Ion Channel; Neuronal Signaling
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
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