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BML-259

BML-259

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-108348-5mg
CASRN	267654-00-2
Available
Product Description	BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Neuroscience-Neurodegeneration
Formula	C14H16N2OS
References	[1].Kaźmierczak A, et al. A novel mechanism of non-Aβ component of Alzheimer's disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5). Neurochem Int. 2011; 58(2):206-214.
MolecularWeight	260.35
Research Area	Neurological Disease
Solubility	DMSO : 125 mg/mL (480.12 mM; Need ultrasonic)
Target	CDK
Pathway	Cell Cycle/DNA Damage

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Amount: 5mg

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Delivery expected until 4/13/2023

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