Comparison

DG-041 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 5mg
Item no. HY-10835-5mg
CASRN 861238-35-9
Available
Product Description
DG-041 is a potent, high affinity and selective EP3 receptor antagonist with IC50s of 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively. DG-041 inhibits PGE2 facilitation of platelet aggregation. DG-041 crosses the blood-brain barrier.
StorageTemperature
Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications
Neuroscience-Neuromodulation
Formula
C23H15Cl4FN2O3S2
References
[1].Singh J, et al. Antagonists of the EP3 receptor for prostaglandin E2 are novel antiplatelet agents that do not prolong bleeding. ACS Chem Biol. 2009 Feb 20; 4(2):115-26. | [2].Hategan G, et al. Heterocyclic 1, 7-disubstituted indole sulfonamides are potent and selective human EP3 receptorantagonists. Bioorg Med Chem Lett. 2009 Dec 1; 19(23):6797-800.
MolecularWeight
592.32
Research Area
Cardiovascular Disease
Solubility
DMSO : 250 mg/mL (422.07 mM; Need ultrasonic)
Target
Prostaglandin Receptor
Isoform
EP3 receptor
Pathway
GPCR/G Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 5mg
Available: In stock
available

Delivery expected until 4/20/2023 

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