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CU-CPT22

CU-CPT22

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	50mg
Item no.	HY-108471-50mg
CASRN	1416324-85-0
Available
Product Description	CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor, and competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 with a Ki of 0.41 µM. CU-CPT22 blocks Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 µM.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-programmed cell death
Formula	C19H22O7
References	[1].Cheng K, et al. Discovery of small-molecule inhibitors of the TLR1/TLR2 complex. Angew Chem Int Ed Engl. 2012 Dec 3; 51(49):12246-9.
MolecularWeight	362.37
Research Area	Cancer
Solubility	DMSO : ≥ 125 mg/mL (344.95 mM)
Target	Toll-like Receptor (TLR)
Pathway	Immunology/Inflammation

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Amount: 50mg

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Delivery expected until 4/13/2023

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