Comparison

Nacubactam European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 50mg
Item no. HY-109008-50mg
CASRN 1452458-86-4
Available
Product Description
Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and class C β-lactamases. Nacubactam (OP0595 free acid) acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs.
StorageTemperature
-20°C, protect from light, stored under nitrogen; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Applications
COVID-19-immunoregulation
Formula
C9H16N4O7S
References
[1].Monogue ML, et al. In Vivo Efficacy of Meropenem with a Novel Non-β-Lactam-β-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model. Antimicrob Agents Chemother. 2018 Aug 27; 62(9). | [2].Livermore DM, et al. Activity of OP0595/β-lactam combinations against Gram-negative bacteria with extended-spectrum, AmpC and carbapenem-hydrolysing β-lactamases. J Antimicrob Chemother. 2015 Nov; 70(11):3032-41.
MolecularWeight
324.31
Research Area
Infection
Solubility
DMSO : 250 mg/mL (770.87 mM; Need ultrasonic) | H2O : 35.71 mg/mL (110.11 mM; Need ultrasonic)
Target
Bacterial
Pathway
Anti-infection

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 50mg
Available: In stock
available

Delivery expected until 4/20/2023 

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