Comparison

Cerivastatin sodium European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 50mg
Item no. HY-109523-50mg
CASRN 143201-11-0
Available
Product Description
Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin sodium reduces low-density lipoprotein cholesterol levels. Cerivastatin sodium also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect.
StorageTemperature
-20°C, protect from light, stored under nitrogen; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Applications
Cancer-Kinase/protease
Formula
C26H33FNNaO5
References
[1].Denoyelle C, et al. Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study. Carcinogenesis. 2001 Aug; 22(8):1139-48. | [2].Stein E, et al. Cerivastatin, a New Potent Synthetic HMG Co-A Reductase Inhibitor: Effect of 0.2 mg Daily in Subjects With Primary Hypercholesterolemia. J Cardiovasc Pharmacol Ther. 1997 Jan; 2(1):7-16. | [3].Furberg CD, et al. Withdrawal of cerivastatin from the world market. Curr Control Trials Cardiovasc Med. 2001; 2(5):205-207.
MolecularWeight
481.53
Research Area
Cancer; Cardiovascular Disease
Solubility
H2O : 100 mg/mL (207.67 mM; ultrasonic and warming and heat to 60°C)
Target
HMG-CoA Reductase (HMGCR); Ferroptosis
Pathway
Metabolic Enzyme/Protease; Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 50mg
Available: In stock
available

Delivery expected until 4/20/2023 

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