Comparison

Rolofylline European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 25 mg
Item no. HY-10965-25mg
CASRN 136199-02-5
eClass 6.1 30220300
eClass 9.0 32160605
Available
Product Description
Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment.Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 (CYP450)[1].Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases[2].
StorageTemperature
-20°C, 3 years (Powder)
Shipping
Blue Ice
Manufacturers Applications
Neuroscience-Neurodegeneration
Molecular Weight
356.46
Clinical Information
Phase 3
Solubility
DMSO : 20 mg/mL (ultrasonic)
Pathway
GPCR/G Protein
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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