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NSC49652

NSC49652

Item no.	HY-111163-10mg
Manufacturer	MedChem Express
CASRN	908563-68-8
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.92
Formula	C14H11NO2
Citations	[1]Goh ETH, et al. A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth. Cell Chem Biol. 2018 Dec 20;25(12):1485-1494.e5.
Smiles	O=C(C1=CC=CC=C1O)/C=C/C2=CC=CN=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	225.247
Product Description	NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 20.83 mg/mL
Manufacturer - Pathway	Apoptosis
Clinical information	No Development Reported

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HY-111163-10mg-safety-datasheet.pdf