« Back
Home /
Zipalertinib

Zipalertinib

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	1 mg
Item no.	HY-112299-1mg
Targets	EGFR
CASRN	1661854-97-2
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Zipalertinib (TAS6417; CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC50 values ranging from 1.1-8.0 nM[1][2].
StorageTemperature	4°C (Powder, protect from light, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	396.44
Clinical_Information	Phase 3
Manufacturers Research_Area	Cancer
Solubility	DMSO : 22.73 mg/mL (ultrasonic)
Isoform	EGFR/ErbB1/HER1
Pathway	Apoptosis; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 mg

available

Request delivery time