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GlyT1 Inhibitor 1

GlyT1 Inhibitor 1

Item no.	HY-112432-5mg
Manufacturer	MedChem Express
CASRN	1820934-93-7
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.59
Citations	[1]Santora VJ, et al. Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties. J Med Chem. 2018 Jul 26;61(14):6018-6033.
Smiles	CC(C)OC1=C(C(N2CC3=CN(C4=CC(C)=NC=C4)N=C3C2)=O)C=C(C#N)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	GlyT
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	387.43
Product Description	GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 25 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Isoform	GlyT1
Clinical information	No Development Reported

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HY-112432-5mg-safety-datasheet.pdf