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Thalidomide-O-amido-PEG2-C2-NH2 (hydrochloride)

Thalidomide-O-amido-PEG2-C2-NH2 (hydrochloride)

Item no.	HY-112617B-50mg
Manufacturer	MedChem Express
CASRN	2376990-30-4
Amount	50 mg
Quantity options	100 mg 1 ea 25 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C21H27ClN4O8
Citations	[1]ARYL SULFONOHYDRAZIDES. WO 2017/176958 A1.
Smiles	O=C(NCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	498.91
Product Description	Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the treatment of cancer[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis; Autophagy; PROTAC
Isoform	Cereblon
Clinical information	No Development Reported

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