Comparison

Debromohymenialdisine European Partner

Item no. HY-113632-1ea
Manufacturer MedChem Express
CASRN 75593-17-8
Amount 1 ea
Quantity options 100 ug 1 ea
Category
Type Inhibitor
Specific against other
Citations [1]Deniz Tasdemir, et al. Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1). J Med Chem. 2002 Jan 17;45(2):529-32.
Smiles NC(N/C1=C2CCNC(C3=C/2C=CN3)=O)=NC1=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 10Z-Debromohymenialdisine
Shipping Condition Room temperature
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
Cancer-Kinase/protease
Manufacturer - Targets
MEK; Raf
Shipping Temperature
Room temperature
Molecular Weight
245.24
Product Description
Debromohymenialdisine (10Z-Debromohymenialdisine) is a pyrrole alkaloid. Debromohymenialdisine has moderate inhibitory activity with an IC50 value of 881 nM in the initial Raf/MEK-1/MAPK signaling cascade assay. Debromohymenialdisine can be used for the research of proliferation and differentiation[1].
Manufacturer - Research Area
Cancer
Solubility
10 mM in DMSO
Manufacturer - Pathway
MAPK/ERK Pathway
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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