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TRPV4 agonist-1

TRPV4 agonist-1

Item no.	HY-114400A-50mg
Manufacturer	MedChem Express
CASRN	2314467-60-0
Amount	50 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Small Molecules
Specific against	other
Citations	[1]Atobe M, et al. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Feb 14;62(3):1468-1483.
Smiles	O=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C(F)C=CC=C51.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	TRP Channel
Shipping Temperature	Room temperature
Molecular Weight	484.93
Product Description	TRPV4 agonist-1 is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Clinical information	No Development Reported

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Amount: 50 mg

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