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Belapectin

Belapectin

Item no.	HY-114440-5mg
Manufacturer	MedChem Express
CASRN	1980787-47-0
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.33
Citations	[1]Sturgill ER, et al. Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity. Oncoimmunology. 2021 Mar 1;10(1):1892265. \|[2]Capasso D, et al. Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach[J]. TrAC Trends in Analytical Chemistry, 2023: 116952.
Smiles	[Belapectin]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GR-MD-02
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Galectin
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Product Description	Belapectin (GR-MD-02) is a Galectin-3 (Gal-3) inhibitor. Belapectin drives tumor-induced immunosuppression by inducing T cell Apoptosis. Belapectin promotes tumor regression and improves survival of tumor-bearing mice through a CD8+ T cell-dependent mechanism. Belapectin binds to Gal-3 with affinity Ki of 2.8 μM[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO: < 1 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O: < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Apoptosis; Immunology/Inflammation
Isoform	Galectin-3
Clinical information	Phase 3

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HY-114440-5mg-safety-datasheet.pdf