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MitoBloCK-10

MitoBloCK-10

Item no.	HY-115467-500ug
Manufacturer	MedChem Express
CASRN	394694-98-5
Amount	500 ug
Quantity options	100 mg 10 mg 1 mg 1 mg x 5 25 mg 500 ug 50 mg 5 mg
Category	Neuroscience Neural Lineage Markers Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.99
Citations	[1]Non Miyata, et al. Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44. J Biol Chem. 2017 Mar 31;292(13):5429-5442.
Smiles	O=C(N/N=C/C1=CC=C([N+]([O-])=O)S1)C2=CC=CC(F)=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	394694-98-5
Similar products	394694-98-5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	HSP
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	293.27
Product Description	MitoBloCK-10 (MB-10) is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity. MitoBloCK-10 (MB-10) inhibits Tim44 (C-terminal domain) binding to the precursor and to Hsp70[1].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-115467-500ug-safety-datasheet.pdf