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Tubulin inhibitor 21

Tubulin inhibitor 21

Item no.	HY-115970-100mg
Manufacturer	MedChem Express
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Andrés F. Yepes, et al. New class of hybrids based on chalcone and melatonin: a promising therapeutic option for the treatment of colorectal cancer. Medicinal Chemistry Research volume 30, pages2240–2255 (2021).
Smiles	O=C(C1=CC=C(C=C1)OCCCSC2=NN=C(O2)CCC3=CNC4=C3C=CC=C4)/C=C/C5=CC=CO5
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Microtubule/Tubulin
Shipping Temperature	Room temperature
Molecular Weight	499.58
Product Description	Tubulin inhibitor 21 (compound 6f), a chalcone- and melatonin- based hybrid, is a potent tubulin inhibitor. Tubulin inhibitor 21 induces a remarkable cytotoxic activity toward SW480 cells (IC50=0.26 μM) with lower effect against nonmalignant cells[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Cell Cycle/DNA Damage; Cytoskeleton
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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