Comparison

AZT triphosphate TEA European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 10mg
Item no. HY-116364A-10mg
Available
Product Description
AZT triphosphate TEA (3'-Azido-3'-deoxythymidine-5'-triphosphate TEA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TEA also inhibits the DNA polymerase of HBV. AZT triphosphate TEA activates the mitochondria-mediated apoptosis pathway.
StorageTemperature
Please store the product under the recommended conditions in the Certificate of Analysis.
Applications
COVID-19-anti-virus
Formula
C10H16N5O13P3.xC6H15N
References
[1].Ryosuke Nomura, et al. Azidothymidine-triphosphate Impairs Mitochondrial Dynamics by Disrupting the Quality Control System. Redox Biol. 2017 Oct; 13:407-417. | [2].Takeya Sato, et al. Engineered Human tmpk/AZT as a Novel Enzyme/Prodrug Axis for Suicide Gene Therapy. Mol Ther. 2007 May; 15(5):962-70. | [3].K Y Hostetler, et al. Enhanced Oral Absorption and Antiviral Activity of 1-O-octadecyl-sn-glycero-3-phospho-acyclovir and Related Compounds in Hepatitis B Virus Infection, in Vitro. Biochem Pharmacol. 1997 Jun 15; 53(12):1815-22.
Research Area
Infection
Target
HIV; DNA/RNA Synthesis; HBV; Reactive Oxygen Species; Apoptosis
Pathway
Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 10mg
Available: In stock
available

Delivery expected until 4/13/2023 

Compare

Add to wishlist

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close