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TLR7 agonist 3

TLR7 agonist 3

Item no.	HY-117602-100mg
Manufacturer	MedChem Express
CASRN	1229024-78-5
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Small Molecules
Specific against	other
Purity	99.90
Citations	[1]Urban Švajger, et al. New antagonists of toll-like receptor 7 discovered through 3D ligand-based virtual screening. Medicinal Chemistry Research. 2015. 24: 362-371.\|[2]Method of treating cancer by targeting myeloid-derived suppressor cells comprising a folate receptor binding ligand attached to a drug via a linker. World Intellectual Property Organization, WO2017205661 A1 2017-11-30.
Smiles	CC(O)(C)CN1C(CCCC)=NC2=C1C3=CC=CC=C3N=C2N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Toll-like Receptor (TLR)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	312.41
Product Description	TLR7 agonist 3 (compound 2) is a TLR7 agonist. TLR7 agonist 3 (compound 5) can be coupled to folate receptor binding ligands to target myeloid-derived suppressor cells and exert anticancer activity[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)\|Ethanol: ≥ 50 mg/mL
Manufacturer - Pathway	Immunology/Inflammation
Isoform	TLR7
Clinical information	No Development Reported

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HY-117602-100mg-safety-datasheet.pdf