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Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Item no.	HY-118594-500mg
Manufacturer	MedChem Express
CASRN	632-93-9
Amount	500 mg
Quantity options	100 g 10 g 10 mM/1 mL 1 g 25 g 500 mg 50 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.79
Citations	[1]Oliva J, et al. Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. Exp Mol Pathol. 2008 Apr;84(2):102-12. \|[2]Mostert V, et al. Serum iron increases with acute induction of hepatic heme oxygenase-1 in mice. Drug Metab Rev. 2007;39(2-3):619-26.
Smiles	CC1C(C(OCC)=O)=C(NC(C)=C1C(OCC)=O)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Biochemical Assay Reagents; Ferrochelatase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	267.32
Product Description	Diethyl 2, 4, 6-trimethyl-1, 4-dihydropyridine-3, 5-dicarboxylate is a ferrochelatase inhibitor that blocks heme synthesis. Diethyl 2, 4, 6-trimethyl-1, 4-dihydropyridine-3, 5-dicarboxylate induces Mallory Denk bodies (MDB) formation. Diethyl 2, 4, 6-trimethyl-1, 4-dihydropyridine-3, 5-dicarboxylate can be used in the fields of iron metabolism, oxidative stress, and liver-related diseases[1][2].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Others
Clinical information	No Development Reported

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HY-118594-500mg-safety-datasheet.pdf