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Vacuolin-1

Vacuolin-1

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	50 mg
Item no.	HY-118630-50mg
CASRN	351986-85-1
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation. Vacuolin-1 can induce vacuole formation and increase the percentage of enucleated cells[1][2][4].
StorageTemperature	-20°C (Powder, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	577.42
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Autophagy; PIKfyve
Pathway	Autophagy; PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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