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MreB Perturbing Compound A22 (hydrochloride)

MreB Perturbing Compound A22 (hydrochloride)

Item no.	HY-118773-25mg
Manufacturer	MedChem Express
CASRN	22816-60-0
Amount	25 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.3
Citations	[1]Zemer Gitai, et al. MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell. 2005 Feb 11;120(3):329-41.\|[2]Noritaka Iwai, et al. Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2. Biosci Biotechnol Biochem. 2002 Dec;66(12):2658-62.
Smiles	ClC1=CC(CSC(N)=N)=CC=C1Cl.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	A22 (hydrochloride)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Molecular Weight	271.59
Product Description	MreB Perturbing Compound A22 hydrochloride is a benzylisothiourea compound that interacts with the ATP binding site of MreB rapidly and reversibly. MreB Perturbing Compound A22 hydrochloride blocks normal rod shape formation and inhibits chromosome partitioning in E. coli, inhibiting growth (MIC=3.1 µg/ml).
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMF: ≥ 20 mg/mL\|DMSO: ≥ 20 mg/mL\|Ethanol: ≥ 1 mg/mL
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

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HY-118773-25mg-safety-datasheet.pdf