Comparison

TDP1 Inhibitor-1 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 5mg
Item no. HY-119372-5mg
CASRN 2248702-80-7
Available
Product Description
TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM.
StorageTemperature
Please store the product under the recommended conditions in the Certificate of Analysis.
Applications
Cancer-programmed cell death
Formula
C26H26N2O5
References
[1].Zhang XR, et al. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents. J Med Chem. 2018 Nov 21; 61(22):9908-9930.
MolecularWeight
446.5
Research Area
Cancer
Target
Phosphodiesterase (PDE)
Pathway
Metabolic Enzyme/Protease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 5mg
Available: In stock
available

Delivery expected until 4/13/2023 

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