Comparison

NaV1.7 inhibitor-1 European Partner

Item no. HY-119934-25mg
Manufacturer MedChem Express
CASRN 1494585-79-3
Amount 25 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.65
Citations [1]Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-GatedSodium Channel (NaV) 1.7 with Potent Analgesic Activity. J Med Chem. 2019 Jan 24;62(2):908-927.
Smiles FC1=CC(OCC2(C)CCC3(CC3)CC2)=C(C4CC4)C=C1C(NS(C5CC5)(=O)=O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Neuroscience-Neuromodulation
Manufacturer - Targets
Sodium Channel
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
435.55
Product Description
NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1].
Manufacturer - Research Area
Neurological Disease
Solubility
DMSO: 100 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway
Membrane Transporter/Ion Channel
Isoform
Nav1.7
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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