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AZ12601011

AZ12601011

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	100 mg
Item no.	HY-122856-100mg
CASRN	2748337-86-0
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4, TGFBR1, and ALK7. AZ12601011 inhibits mammary tumor growth [1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	313.36
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 5 mg/mL (ultrasonic)
Manufacturers Target	TGF-β Receptor
Isoform	ALK4; ALK7
Pathway	TGF-beta/Smad
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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