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Kurarinol

Kurarinol

Item no.	HY-122933-1ea
Manufacturer	MedChem Express
CASRN	855746-98-4
Amount	1 ea
Quantity options	10mg 1 ea 25mg 5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Y B Ryu, et al. Kurarinol, tyrosinase inhibitor isolated from the root of Sophora flavescens. Phytomedicine. 2008 Aug;15(8):612-8. [2]Guangwen Shu, et al. Kurarinol induces hepatocellular carcinoma cell apoptosis through suppressing cellular signal transducer and activator of transcription 3 signaling. Toxicol Appl Pharmacol. 2014 Dec 1;281(2):157-65. [3]Hyun Young Kim, et al. Hypolipidemic effects of Sophora flavescens and its constituents in poloxamer 407-induced hyperlipidemic and cholesterol-fed rats. Biol Pharm Bull. 2008 Jan;31(1):73-8.
Smiles	CC([C@H](CCC(C)(O)C)CC(C(O)=C1)=C(O[C@H](C(C=CC(O)=C2)=C2O)CC3=O)C3=C1OC)=C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Tyrosinase
Shipping Temperature	Room temperature
Molecular Weight	456.53
Product Description	Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase[1].
Manufacturer - Research Area	Cancer; Cardiovascular Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis; Metabolic Enzyme/Protease
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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