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SGC-AAK1-1

SGC-AAK1-1

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	25mg
Item no.	HY-123940-25mg
CASRN	2247894-32-0
Available
Product Description	SGC-AAK1-1 is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC50 of 270 nM and a Ki of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-Kinase/protease
Formula	C21H25N5O3S
References	[1].Agajanian MJ, et al. WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Rep. 2019 Jan 2; 26(1):79-93.e8.
MolecularWeight	427.52
Research Area	Cancer
Solubility	DMSO : 50 mg/mL (116.95 mM; ultrasonic and warming and heat to 60°C)
Target	Others
Pathway	Others

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Amount: 25mg

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Delivery expected until 4/6/2023

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