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Adenosine-2'-monophosphate

Adenosine-2'-monophosphate

Item no.	HY-124151-5mg
Manufacturer	MedChem Express
CASRN	130-49-4
Amount	5 mg
Quantity options	10 mg 1 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.91
Citations	[1]Jackson EK, Gillespie DG, Dubey RK. 2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. J Pharmacol Exp Ther. 2011;337(2):444‐450.\|[2]Newell EA, Exo JL, Verrier JD, et al. 2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors. Brain Res. 2015;1594:27‐35.
Smiles	O=[P](O)(O)O[C@H]([C@@H]1O)[C@@](N2C3=NC=NC(N)=C3N=C2)([H])O[C@@H]1CO
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2'-AMP,Adenosine 2'-phosphate,AMP 2'-phosphate
Shipping Condition	Cool pack
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Adenosine Receptor; Endogenous Metabolite
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	347.22
Product Description	Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’, 3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’, 3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A2A receptor activation[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 62.5 mg/mL (ultrasonic; warming; heat to 80°C)\|H2O: 50 mg/mL (ultrasonic; adjust pH to 7 with NaOH)
Manufacturer - Pathway	GPCR/G Protein; Metabolic Enzyme/Protease
Isoform	Human Endogenous Metabolite
Clinical information	No Development Reported

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HY-124151-5mg-safety-datasheet.pdf