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Z-Ile-Leu-aldehyde

Z-Ile-Leu-aldehyde

Item no.	HY-12465-1mg
Manufacturer	MedChem Express
CASRN	161710-10-7
Amount	1 mg
Quantity options	10 mM/1 mL 10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Reem Suleiman, et al. The Role Of Notch In Th17 Differentiation. University of Massachusetts Amherst. 9-2013.\|[2]Schwarzer R, et al. Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model. Blood Cancer J. 2014 Jun 13;4:e217.
Smiles	O=C(OCC1=CC=CC=C1)N[C@H](C(N[C@H](C=O)CC(C)C)=O)[C@@H](C)CC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Z-IL-CHO,GSI-XII,γ-Secretase inhibitor XII
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Notch; γ-secretase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	362.46
Product Description	Z-Ile-Leu-aldehyde (Z-IL-CHO) is a potent and competitive peptide aldehyde inhibitor of γ-secretase and notch[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 41 mg/mL
Manufacturer - Pathway	Apoptosis; Neuronal Signaling; Stem Cell/Wnt
Clinical information	No Development Reported

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