G0507

Item no.	HY-124658-100mg
Manufacturer	MedChem Express
CASRN	1223998-29-5
Amount	100 mg
Quantity options	100 mg 10 mg 1 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.85
Citations	[1]Nickerson NN, et al. A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria. Antimicrob Agents Chemother. 2018 Mar 27;62(4).
Smiles	O=C1NC(NC(C2=CC=C(C)S2)=C3C4=CC=C(OC)C=C4)=C3C(N1)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1223998-29-5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	353.40
Product Description	G0507, a pyrrolopyrimidinedione compound, is a potent LolCDE ABC Transporter inhibitor. G0507 is a inhibitor of Escherichia coli growth and induces the extracytoplasmic σE stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria[1].
Manufacturer - Research Area	Infection
Solubility	DMF: 10 mg/mL (ultrasonic; warming; heat to 60°C)\|DMSO: 5 mg/mL (ultrasonic)\|H2O: < 0.1 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

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HY-124658-100mg-safety-datasheet.pdf