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DB2115 (tertahydrochloride)

DB2115 (tertahydrochloride)

Item no.	HY-124676A-100mg
Manufacturer	MedChem Express
CASRN	1366126-19-3
Amount	100 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.13
Citations	[1]W. David Wilson, et al. Pu.1 inhibitors. Patent WO2017223260A1. 2017-12-28.
Smiles	N=C(C1=CC=C2N=C(C3=CC=C(OCCCCOC4=CC=C(C5=NC6=CC=C(C(N)=N)C=C6N5)C=C4)C=C3)NC2=C1)N.[H]Cl.[H]Cl.[H]Cl.[H]Cl
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	704.48
Product Description	DB2115 tetrahydrochloride is a highly selective PU.1 inhibitor that suppresses the binding of PU.1 to DNA (IC50: 2.3 nM). DB2115 tetrahydrochloride can inhibit tumor cell proliferation and induce apoptosis. DB2115 tetrahydrochloride can be used in the research of tumors such as leukemia[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 15.85 mg/mL (ultrasonic; warming; adjust pH to 4 with HCl; heat to 60°C)
Manufacturer - Pathway	Apoptosis
Clinical information	No Development Reported

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HY-124676A-100mg-safety-datasheet.pdf