Comparison

δ-Secretase inhibitor 11 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 50 mg
Item no. HY-124832-50mg
CASRN 842964-18-5
eClass 6.1 30220300
eClass 9.0 32160605
Available
Product Description
δ-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific δ-secretase inhibitor, with an IC50 of 0.7 μM. δ-Secretase inhibitor 11 interacts with both the active site and allosteric site of δ-secretase. δ-Secretase inhibitor 11 attenuates tau and APP (amyloid precursor protein) cleavage. δ-Secretase inhibitor 11 ameliorates synaptic dysfunction and cognitive impairments in tau P301S and 5XFAD transgenic mouse models. δ-Secretase inhibitor 11 can be used for Alzheimer's disease research[1].
StorageTemperature
4°C (Powder, protect from light)
Shipping
Room Temperature
Manufacturers Applications
Neuroscience-Neurodegeneration
Molecular Weight
220.23
Clinical Information
No Development Reported
Solubility
DMSO : 125 mg/mL (ultrasonic)
Isoform
Caspase 3; Caspase 8
Pathway
Apoptosis; Neuronal Signaling
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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