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PI3Kδ-IN-3

PI3Kδ-IN-3

Item no.	HY-125376-1ea
Manufacturer	MedChem Express
CASRN	1431540-99-6
Amount	1 ea
Quantity options	1 ea 1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C28H24N6O3
Citations	[1]Hoegenauer K, et al. Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors. ACS Med Chem Lett. 2016 Jun 2;7(8):762-7.
Smiles	N#CC1=CC(C2=CC3=C(C4=CC=CC(C(N5CCN(C(C)=O)CC5)=O)=C4)N=CN=C3C=C2)=CN=C1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	PI3K
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	492.53
Product Description	PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	PI3K/Akt/mTOR
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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