PCTR1

Item no.	HY-125445-10ug
Manufacturer	MedChem Express
CASRN	1810710-59-8
Amount	10 ug
Quantity options	100 mg 10 ug 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Sesquile Ramon, et al. The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation. Am J Pathol. 2016 Apr;186(4):962-73.\|[2]Brian E Sansbury, et al. PCTR1 Enhances Repair and Bacterial Clearance in Skin Wounds. Am J Pathol. 2021 Jun;191(6):1049-1063.\|[3]Yong-Jian Liu, et al. PCTR1 ameliorates lipopolysaccharide-induced acute inflammation and multiple organ damage via regulation of linoleic acid metabolism by promoting FADS1/FASDS2/ELOV2 expression and reducing PLA2 expression. Lab Invest. 2020 Jul;100(7):904-915.
Smiles	CC/C=C\C[C@@H]([C@@H](/C=C/C=C/C=C\C/C=C\C/C=C\CCC(O)=O)SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial
Shipping Temperature	Room temperature
Molecular Weight	649.80
Product Description	PCTR1 is a potent monocyte/macrophage agonist, regulating key anti-inflammatory and pro-resolving processes during bacterial infection. PCTR1 is a member of the protectin family of specialized pro-resolving mediators (SPMs)[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

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