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VHL Ligand-Linker Conjugates 15

VHL Ligand-Linker Conjugates 15

Item no.	HY-125906-1ea
Manufacturer	MedChem Express
CASRN	2375564-62-6
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.
Smiles	O=C(NCC1=CC=C(C=C1OCCOC2=CC=C(C=C2)C3OCCO3)C4=C(N=CS4)C)[C@H]5N(C[C@@H](C5)O)C([C@H](C(C)(C)C)NC(C6(CC6)F)=O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	E3 Ligase Ligand-Linker Conjugates 56
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	E3 Ligase Ligand-Linker Conjugates
Shipping Temperature	Room temperature
Molecular Weight	724.84
Product Description	VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	PROTAC
Isoform	von Hippel-Lindau (VHL)
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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