AN3661

Item no.	HY-128204-25mg
Manufacturer	MedChem Express
CASRN	1268335-33-6
Amount	25 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.89
Formula	C10H11BO4
Citations	[1]Sonoiki E, et al. A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue. Nat Commun. 2017;8:14574. Published 2017 Mar 6.
Smiles	O=C(O)CCC1=C(B(O)OC2)C2=CC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Parasite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	206.00
Product Description	AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM), Ugandan field isolates (mean ex vivo IC50=64 nM), and murine P. berghei and P. falciparum infections[1].
Manufacturer - Research Area	Infection
Solubility	DMSO : 250 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Isoform	Plasmodium
Clinical information	No Development Reported

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HY-128204-25mg-safety-datasheet.pdf