AN3661

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	25mg
Item no.	HY-128204-25mg
CASRN	1268335-33-6
Available
Product Description	AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM), Ugandan field isolates (mean ex vivo IC50=64 nM), and murine P. berghei and P. falciparum infections.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	COVID-19-immunoregulation
Formula	C10H11BO4
References	[1].Sonoiki E, et al. A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue. Nat Commun. 2017; 8:14574. Published 2017 Mar 6.
MolecularWeight	206.0
Research Area	Infection
Solubility	DMSO : 250 mg/mL (1213.59 mM; Need ultrasonic)
Target	Parasite
Pathway	Anti-infection

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Delivery expected until 4/20/2023

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