M‑89

Item no.	HY-128347-25mg
Manufacturer	MedChem Express
CASRN	2363165-42-6
Amount	25 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.14
Citations	[1]Aguilar A, et al. Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction. J Med Chem. 2019 Jul 11;62(13):6015-6034.
Smiles	O=C(NC)O[C@@H]1[C@@H]([C@]2(C3CCN(CC4CN(C5=CC=C(S(=O)(C6=CC=NC=C6)=O)C=C5)C4)CC3)CN(C)CC7=C2C=CC=C7)CCC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2363165-42-6
Similar products	2363165-42-6
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Epigenetic Reader Domain
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	657.87
Product Description	M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia[1].
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO: 7.35 mg/mL (ultrasonic)
Manufacturer - Pathway	Epigenetics
Clinical information	No Development Reported

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HY-128347-25mg-safety-datasheet.pdf