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TAS4464

TAS4464

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	25mg
Item no.	HY-128586-25mg
CASRN	1848959-10-3
Available
Product Description	TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-programmed cell death
Formula	C21H23FN6O6S
References	[1].Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.
MolecularWeight	506.51
Research Area	Cancer
Solubility	DMSO : 40 mg/mL (78.97 mM; Need ultrasonic)
Target	NEDD8-activating Enzyme
Pathway	Metabolic Enzyme/Protease

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Amount: 25mg

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Delivery expected until 4/13/2023

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