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2-Hydroxy atorvastatin (calcium salt)

2-Hydroxy atorvastatin (calcium salt)

Item no.	HY-128828-5mg
Manufacturer	MedChem Express
CASRN	265989-46-6
Amount	5 mg
Quantity options	10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.01
Citations	[1]Borek-Dohalský V, et al. Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study. Anal Bioanal Chem. 2006 Sep;386(2):275-85.
Smiles	FC1=CC=C(C2=C(C3=CC=CC=C3)C(C(NC4=CC=CC=C4O)=O)=C(C(C)C)N2CC[C@@H](O)C[C@@H](O)CC(O)=O)C=C1.[Ca].[1/2]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Drug Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	594.69
Product Description	2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: 12.5 mg/mL (ultrasonic; adjust pH to 3 with HCl)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-128828-5mg-safety-datasheet.pdf