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FITC-Dextran (MW 4000)

FITC-Dextran (MW 4000)

Item no.	HY-128868A-10mg
Manufacturer	MedChem Express
CASRN	60842-46-8
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	Biochem Biophys Res Commun. 2020 Dec 17;533(4):1276-1282. Biochem Biophys Res Commun. 2024 Sep 3:723:150176. Bioengineered. 2022 Feb;13(2):3680-3693. Bioengineered. 2022 Mar;13(3):7209-7220. Biomaterials. 1 June 2022, 121608. Biomed Pharmacother. 2024 Apr 25:175:116633. Brain Behav Immun. 2023 Feb 27;S0889-1591(23)00050-8. Cell Rep. 2023 Apr 4;42(4):112346. Cell Rep. 2023 Jun 20;42(7):112660. Curr Issues Mol Biol. 2022 Nov 29;44(12):5995-6005. Device. 2024 June 12 EBioMedicine. 2022 Jul 28;82:104181. Exp Brain Res. 2021 Jan;239(1):341-350. FEBS J. 2024 Sep 15. Food Funct. 23rd October 2021. Front Pharmacol. 02 November 2021. Gut Microbes. 2024 Jan-Dec;16(1):2377576. Int Immunopharmacol. 2024 May 23:135:112263. J Ethnopharmacol. 2023 Aug 26;117098. J Ethnopharmacol. 2023 Dec 18:117567. J Ethnopharmacol. 2024 Oct 16;337(Pt 3):118937. Mol Med Rep. 2024 Jun;29(6):90. Mol Neurobiol. 2024 Oct 17. Mucosal Immunol. 2024 Sep 6:S1933-0219(24)00093-X. Neurotox Res. 2022 May 7. Pharmacol Res. 2024 May 21:205:107229. Phytomedicine. 2023 Apr 21, 154825. Res Sq. 2024 Aug 13. Research Square Preprint. 2023 Oct 10. Research Square Preprint. 2023 Oct 23. Research Square Preprint. 2024 Apr 9. Sci Adv. 2023 Oct 20;9(42):eadi0699. Adv Sci (Weinh). 2021 Aug 16;e2101912. Cancer Lett. 2024 Apr 16:591:216897. Cell Tissue Res. 2022 Jul 4. Ecotoxicol Environ Saf. 2024 Aug 16:284:116874. Ecotoxicol Environ Saf. 2024 Jul 23:282:116762. Exp Brain Res. 2021 Jan;239(1):341-350. Front Pharmacol. 2024 Aug 29:15:1428572. Heliyon. 2023 Jul 13. Immun Inflamm Dis. 07 September 2022. Immun Inflamm Dis. 2024 Dec;12(12):e70107. Immunobiology. 2022: 152315. J Funct Foods. 2024 Nov. J Steroid Biochem Mol Biol. 2023 Apr 21;106314. J Tradit Complement Med. 2024 Apr 29. J Transl Med. 2024 Jun 5;22(1):535. Kaohsiung J Med Sci. 2024 Jun 5. Nat Commun. 2024 Jan 19;15(1):613. Nat Metab. 2022 Sep;4(9):1138-1149. Research Square Print. 2023 Feb 23. SSRN. 2023 Jun 12. Theranostics. 2023; 13(6):2040-2056. [1]Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15. [2]Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017;1594:179-189. [3]Moumaris M, et al. Fluorescein isothiocyanate-dextran can track apoptosis and necrosis induced by heat shock of peripheral blood mononuclear cells and HeLa cells[J]. Open Biological Sciences Journal, 2015, 1(1). [4]Okabayashi K, et al. Cdc42 activates paracellular transport in polarised submandibular gland cells. Arch Oral Biol. 2021 Dec;132:105276. [5]Yu W, et al. ACE2 contributes to the maintenance of mouse epithelial barrier function. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1276-1282.
Smiles	[FITC-Dextran<br /> (MW 4000)]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	60842-46-8
Similar products	60842-46-8
Shipping condition	Room temperature
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Targets	Fluorescent Dye
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	4000.00(Average)
Product Description	FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3].
Manufacturer - Research Area	Others
Solubility	DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 16.67 mg/mL (ultrasonic)
Manufacturer - Pathway	Others
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-128868A-10mg-safety-datasheet.pdf