YMU1

Item no.	HY-129125-10mg
Manufacturer	MedChem Express
CASRN	902589-96-2
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.00
Formula	C17H22N4O4S
Citations	[1]Hu CM, et al. Tumor cells require thymidylate kinase to prevent dUTP incorporation during DNA repair. Cancer Cell. 2012 Jul 10;22(1):36-50. [2]Fengqiang Yu, et al. Knockdown of DTYMK suppresses progression and EMT of lung adenocarcinoma 1 via STAT3 signaling. Europe PMC. 20 Mar 2023, 55(5):213-221.
Smiles	O=C(N1CCN(C(CN2SC3=NC(C)=CC(C)=C3C2=O)=O)CC1)OCC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Others; STAT
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	378.45
Product Description	YMU1 is a selective inhibitor of human thymidylate kinase (hTMPK) with an IC50 of 610 nM. YMU1 inhibits tumor proliferation[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 5.56 mg/mL (ultrasonic; warming; heat to 70°C)
Manufacturer - Pathway	JAK/STAT Signaling; Others; Stem Cell/Wnt
Isoform	STAT3
Clinical information	No Development Reported

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HY-129125-10mg-safety-datasheet.pdf