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TrkA-IN-1

TrkA-IN-1

Item no.	HY-129634-10mM
Manufacturer	MedChem Express
CASRN	1680179-43-4
Amount	10 mM/1 mL
Quantity options	10 mM/1 mL 10 mg 25 mg 5 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Inhibitors & Compound Libraries Small Molecules By Organ Thyroid Cancer
Type	Inhibitors
Specific against	other
Purity	96.46
Citations	[1]Su HP , et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306.
Smiles	O=C(NC1=CN=C(C)N=C1C2=CC=CC=C2)NC3C4=C(C5=C3C=CC=C5)C=CC=C4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1680179-43-4
Similar products	1680179-43-4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Trk Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	392.45
Product Description	TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 8.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Neuronal Signaling; Protein Tyrosine Kinase/RTK
Isoform	TrkA; TrkB; TrkC
Clinical information	No Development Reported

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HY-129634-10mM-safety-datasheet.pdf