Comparison

Seco-Duocarmycin TM European Partner

Item no. HY-130083-1ea
Manufacturer MedChem Express
CASRN 236102-87-7
Amount 1 ea
Quantity options 100 mg 1 ea 25 mg
Category
Type Inhibitor
Specific against other
Citations [1]Gieseg MA, et al. Comparison of the patterns of DNA alkylation by phenol and amino seco-CBI-TMI compounds: use of a PCR method for the facile preparation of single end-labelled double-stranded DNA. Anticancer Drug Des. 1999 Feb;14(1):77-84.
Smiles OC[C@H]1C2=C(C=CC=C3)C3=C(O)C=C2N(C(C4=CC(C=C(OC)C(OC)=C5OC)=C5N4)=O)C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
ADC Related
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
ADC Cytotoxin; DNA Alkylator/Crosslinker
Shipping Temperature
Room temperature
Molecular Weight
448.47
Product Description
Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC)[1].
Manufacturer - Research Area
Cancer
Solubility
10 mM in DMSO
Manufacturer - Pathway
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Isoform
Duocarmycins
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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