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Olodanrigan

Olodanrigan

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	100 mg
Item no.	HY-13106-100mg
Targets	Angiotensin Receptor
CASRN	1316755-16-4
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons[1][2][3][4].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	507.58
Clinical_Information	Phase 2
Manufacturers Research_Area	Neurological Disease; Endocrinology
Solubility	DMSO : ≥ 34 mg/mL\|H2O : < 0.1 mg/mL
Manufacturers Target	Angiotensin Receptor
Isoform	AT2 Receptor
Pathway	GPCR/G Protein
Manufacturers Product type	Reference compound

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HY-13106-100mg-safety-datasheet.pdf