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(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

Item no.	HY-131168-25mg
Manufacturer	MedChem Express
CASRN	2086301-47-3
Amount	25 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.31
Citations	[1]Yimin Qian, et al. Compounds and methods for the targeted degradation of bromodomain-containing proteins. WO2017030814A1.\|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-991.
Smiles	O=C(CN1CCC(O[C@H]2C[C@H](NC(OC(C)(C)C)=O)C2)CC1)N[C@H](C(N([C@H](C(N[C@@H](C)C3=CC=C(C=C3)C4=C(C)N=CS4)=O)C5)C[C@@H]5O)=O)C(C)(C)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	E3 Ligase Ligand-Linker Conjugates
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	754.98
Product Description	(S, R, S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) is a E3 ligase ligand-linker conjugate that contains on one end a VHL ligand. (S, R, S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is used in PROTAC technology[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	PROTAC
Isoform	von Hippel-Lindau (VHL)
Clinical information	No Development Reported

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HY-131168-25mg-safety-datasheet.pdf