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AMPK activator 4

AMPK activator 4

Item no.	HY-131334-5mg
Manufacturer	MedChem Express
CASRN	2493239-46-4
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Oncology Metabolism By Cell Type Hematology Lymphoma Cell Biology Obesity Cell Status Autophagy Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.18
Citations	[1]Sun G, You Y, Li H, et al. Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I. Eur J Med Chem. 2020;200:112466.
Smiles	CC(C)(OC1=CC=C(Cl)C=C1)C(NC2=CC=C(OCC3=CC=C(C#N)C=C3)C=C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2493239-46-4
Similar products	2493239-46-4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	AMPK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	420.89
Product Description	AMPK activator 4 is a potent AMPK activator without inhibition of mitochondrial complex I. AMPK activator 4 selectively activates AMPK in the muscle tissues. AMPK activator 4 dose-dependently improves glucose tolerance in normal mice, and significantly lowers fasting blood glucose level and ameliorates insulin resistance in db/db diabetic mice. Anti-hyperglycemic effect[1].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: 250 mg/mL (ultrasonic)
Manufacturer - Pathway	Epigenetics; PI3K/Akt/mTOR
Clinical information	No Development Reported

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HY-131334-5mg-safety-datasheet.pdf