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Disufenton sodium

Disufenton sodium

Item no.	HY-13244-5mg
Manufacturer	MedChem Express
CASRN	168021-79-2
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.97
Formula	C11H13NNa2O7S2
Citations	[1]Kuroda S, et al. Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat. J Cereb Blood Flow Metab, 1999, 19(7), 778-787. [2]Marshall JW, et al. NXY-059, a free radical--trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species. Stroke, 2001, 32(1), 190-198. [3]Culot M, et al. Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. Brain Res, 2009, 19(1294), 144-152.
Smiles	O=S(C1=C(C=CC(S(=O)(O[Na])=O)=C1)/C=[N+]([O-])/C(C)(C)C)(O[Na])=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NXY-059
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Reactive Oxygen Species
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	381.33
Product Description	Disufenton sodium (NXY-059) scavenges free radicals, reduces ischemic damage and exhibits neuroprotective effects[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : ≥ 50 mg/mL
Manufacturer - Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Clinical information	Phase 3

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HY-13244-5mg-safety-datasheet.pdf