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Tadnersen

Tadnersen

Item no.	HY-132581-1ea
Manufacturer	MedChem Express
CASRN	2170507-65-8
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	90.06
Citations	[1]Smeyers J, et al. C9ORF72: What It Is, What It Does, and Why It Matters. Front Cell Neurosci. 2021;15:661447. Published 2021 May 5.\|[2]Aoki Y, et al. Emerging Oligonucleotide Therapeutics for Rare Neuromuscular Diseases [published online ahead of print, 2021 Jun 3]. J Neuromuscul Dis. 2021;10.3233/JND-200560.
Smiles	[Tadnersen]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	BIIB078,IONIS-C9Rx
Shipping Condition	Cool pack
Available
Manufacturer - Type	Oligonucleotides
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Others; Ras
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Product Description	Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion[1].
Manufacturer - Research Area	Neurological Disease
Solubility	H2O: ≥ 100 mg/mL
Manufacturer - Pathway	GPCR/G Protein; MAPK/ERK Pathway; Others
Clinical information	Phase 3

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-132581-1ea-safety-datasheet.pdf