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Afatinib N-Oxide

Afatinib N-Oxide

Item no.	HY-133110-1ea
Manufacturer	MedChem Express
CASRN	2413212-11-8
Amount	1 ea
Quantity options	1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Pawan kumar, et al. A controlled, efficient and robust process for the synthesis of an epidermal growth factor receptor inhibitor: Afatinib Dimaleate. Chem Rep, 2019, 1(1): 3-12.
Smiles	ClC1=C(F)C=CC(NC2=NC=NC3=C2C=C(NC(/C=C/C[N+](C)([O-])C)=O)C(O[C@H]4CCOC4)=C3)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Drug Metabolite
Shipping Temperature	Room temperature
Molecular Weight	501.94
Product Description	Afatinib N-Oxide is an impurity of Afatinib dimaleate in oxidative degradation. Afatinib dimaleate is an irreversible EGFR family inhibitor[1].
Manufacturer - Research Area	Others
Solubility	10 mM in DMSO
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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