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PDD00017238

PDD00017238

Item no.	HY-133530-50mg
Manufacturer	MedChem Express
CASRN	1952247-05-0
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.71
Citations	[1]Dominic I James, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190.
Smiles	O=S(C1=CC=C(N2CC3=C(C)N=C(C)S3)C(N(C4=NC=NS4)C2=O)=C1)(NC5(C)CC5)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Poly(ADP-ribose) Glycohydrolase (PARG)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	476.60
Product Description	PDD00017238 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with EC50 values of 40 nM and 55 nM in biochemical assay and cell POM, respectively[1].
Manufacturer - Research Area	Others
Solubility	DMSO: 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	No Development Reported

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HY-133530-50mg-safety-datasheet.pdf